Thanks everyone again for all the info and insights.
This got me thinking:
I'm wondering if I can do a combination now... running my small silencer boxes for the return on each leaf, 6 runs of them... 3 along each side of the room (6x36" cross sectional area = 216"... I know that's not the right number, but I was thinking I could get away with 5 changes per hour instead of 6, in which case this would be large enough of a cross sectional area, and a low enough velocity), and have them vent out on the east wall. I spoke with my contractor and he doesn't think the large boxes on the East Wall (the wall with my supply boxes in my previous post) will fly with the inspector due to setback requirements. Instead I could utilize the pool room next door for the supply boxes on both leaves as you suggested... bumping out my outer leaf wall to accommodate the larger boxes. This would put my supply register in the front right corner of the room, but I could duct it to the front central bottom of my baffle, and then have multiple return registers on the ceiling in the rear of the room. I feel like this works for HVAC, but I can't help but think it might not work well for preserving my isolation as I'll be taking out a lot of my spring volume in my MSM system to accommodate 12 silencer boxes. I might consider shortening the boxes to allow for more spring area of just insulation... There would still be 6 inches of spring from the insulation on the inner leaf with this design though. Also, cutting that many openings for registers in my double layers of drywall seems mental... Something like this is what I was thinking: Interested in if anyone has any thoughts on if this is indeed a bad idea. Failing that, at some point I might just have to back off of my isolation requirements as a compromise and work around noise levels at different times of the day... and resort to one silencer per opening that penetrates both leaves via a massive wooden duct. Thanks, AaronFilling your joist cavities decreases the gap in your MSM system, but for many of us, there's no other choice. I haven't done the math to see if this is feasible, but with that in mind, did you ever consider running 2 or 3 sets of your long joist cavity style silencers down each side of your room? One side being supply, the other being return. You could have your outer leaf silencers mounted on the outside of your room (like the supply silencer in your recent picture). They could have 2 or 3 sleeves on them that would connect to the inner leaf silencers (these would be the long skinny joist cavity style).