Venting computer iso box into room or ventilation system

I'm building a room about 1,500 cubic feet with a ventilation system exhausting (warm) room air and bringing in fresh air, with an industrial fan. My original plan was to tie a DIY computer etc. iso box into the ventilation ducting, with a smaller (quiet) fan always running in the exhaust duct of the iso box (when equipment in the box is on, that is). The reason for the smaller fan is that I wouldn't always have the main system on. Because of space constraints, tying the iso box into the ducting is presenting some installation issues, so I'm considering exhausting the iso box into the room. I may consider purchasing a pro designed one (mainly due to the engineered acoustics) if I go this route; price seems to be about $1500. If I build my own box, and tie it into the main duct system, the iso fan noise is less of an issue, because the latter has long run insulated ducting. I'm currently using a laptop, and will have powered, fanless, speakers, and currently have no other gear with fans. The iso box would be in case I get a tower computer, etc. I'm mainly doing voice recording; I'll do a bit of small scale music production mostly for fun. Looking for feedback on the two methods. Thanks. Bob

I fought with a box/rack design for a while. I finally decided to convert my PC to water-cooled. I am absolutely satisfied with the results. It is dead quiet. If it weren't for the screens, I wouldn't even know it was on. I used the Zalman Reserator 1 v2 cooler: http://www.xoxide.com/zalman-reserator-1-v2.html There are two basic fears people have about liquid cooling - leakage and pump failure. On the leakage subject, the unit seems very well built and not prone to ever do such a thing, but time will tell I suppose. The pump will eventually fail, but I have a temp monitoring program that will shut the thing down before damage can occur, so I feel good about it. We are definitely talking quiet. Best decision I ever made.